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Comment from Michael N. of Taquería Auténtica Business Owner
5/11/2016

I have been meaning to try this place among a few that are nestled near the corner of Broad and Watchung in Bloomfield. A friend mentioned that it had extremely good tacos.Wow does it live up to the name. Fantastic fresh guac and chips (my wife said some of the best she's ever had and she's a huge guac aficionado. It had little chunks of some kind of hot pepper in it that were delicious). We tried the following tacos: carnitas, chorizo, nopalitos (cactus), and hungos (mushroom). All were very different and very delicious. The carnitas has wonderful stewed, marinated flavor from the citrus, served with not much more garnish than a little wedge of lime. The hungos was light and delicate, as were the nopalitos. The chorizo has a creamy, very spicy sauce and packs and oily wallop.This place compares favorably to good tacos I've had in Brooklyn, Austin, and Mexico. Highly recommended to the fan of the 'authentic' Mexican style with the two soft tortillas.Decor is very casual and friendly - eclectic mix of art on the walls. An appropriate vibe for the cuisine. And the price is right!

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444 reviews
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said "My husband and I LOVE Mexican Food and once we found this place we stopped going anywhere else. With every meal you order you can expect to take home leftovers and their prices are extremely fair and…" read more
in Mexican
169 reviews
said "My husband and I stopped at this family-owned whole-in-the-wall fast casual restaurant on our way to visit relatives who live far away, and I think this was the first time that we were so impressed by a…" read more
in Latin American, Mexican
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We specialize in serving traditional Mexican food not typically found at other Mexican restaurants. Winner, Best Tacos, Newark Star-Ledger Munchmobile, June 2013.

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Research Articles, Neurobiology of Disease
Petra Fischer , Chiung Chu Chen , Ya Ju Chang , Chien-Hung Yeh , Alek Pogosyan , Damian M. Herz , Binith Cheeran , Alexander L. Green , Tipu Z. Aziz , Jonathan Hyam , Simon Little , Thomas Foltynie , Patricia Limousin , Ludvic Zrinzo , Harutomo Hasegawa , Michael Samuel , Keyoumars Ashkan , Peter Brown and Huiling Tan
Journal of Neuroscience 14 May 2018, 3596-17; DOI: https://doi.org/10.1523/JNEUROSCI.3596-17.2018
Petra Fischer
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Chiung Chu Chen
Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital, 333, Linkou, Taipei, Taiwan
Ya Ju Chang
Department of Physical Therapy, Graduate Institute of Rehabilitation Science, Chang Gung University, 333, Taipei, Taiwan
Chien-Hung Yeh
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital, 333, Linkou, Taipei, Taiwan
Alek Pogosyan
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Damian M. Herz
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Binith Cheeran
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Alexander L. Green
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Tipu Z. Aziz
Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Jonathan Hyam
Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, WC1N 3BG, London, United Kingdom.
Simon Little
Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, WC1N 3BG, London, United Kingdom.
Thomas Foltynie
Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, WC1N 3BG, London, United Kingdom.
Patricia Limousin
Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, WC1N 3BG, London, United Kingdom.
Ludvic Zrinzo
Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, WC1N 3BG, London, United Kingdom.
Harutomo Hasegawa
Departments of Neurology and Neurosurgery, King's College Hospital, King's College London, SE5 9RS, London, United Kingdom.
Michael Samuel
Departments of Neurology and Neurosurgery, King's College Hospital, King's College London, SE5 9RS, London, United Kingdom.
Keyoumars Ashkan
Departments of Neurology and Neurosurgery, King's College Hospital, King's College London, SE5 9RS, London, United Kingdom.
Peter Brown
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.
Huiling Tan
Medical Research Council Brain Network Dynamics Unit at the sUniversity of Oxford, OX1 3TH, Oxford, United Kingdom. Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, Oxford, United Kingdom.

Abstract

Gait disturbances in Parkinson's disease are commonly refractory to current treatment options and majorly impair patient's quality of life. Auditory cues facilitate gait and prevent motor blocks. We investigated how neural dynamics in the human subthalamic nucleus of Parkinsons's disease patients (14 male, 2 female) vary during stepping and whether rhythmic auditory cues enhance the observed modulation. Oscillations in the beta band were suppressed after ipsilateral heel strikes, when the contralateral foot had to be raised, and re-appeared after contralateral heel strikes, when the contralateral foot rested on the floor. The timing of this 20-30 Hz beta modulation was clearly distinct between the left and right subthalamic nucleus, and was alternating within each stepping cycle. This modulation was similar, whether stepping movements were made while sitting, standing, or during gait, confirming the utility of the stepping in place paradigm. During stepping in place beta modulation increased with auditory cues that assisted patients in timing their steps more regularly. Our results suggest a link between the degree of power modulation within high beta frequency bands and stepping performance. These findings raise the possibility that alternating deep brain stimulation patterns may be superior to constant stimulation for improving Parkinsonian gait.

SIGNIFICANCE STATEMENT

Gait disturbances in Parkinson's disease majorly reduce patients' quality of life and are often refractory to current treatment options. We investigated how neural activity in the subthalamic nucleus of patients who received deep brain stimulation surgery covaries with the stepping cycle. 20-30Hz beta activity was modulated relative to each step, alternating between the left and right STN. The stepping performance of patients improved when auditory cues were provided, which went along with enhanced beta modulation. This raises the possibility that alternating stimulation patterns may also enhance beta modulation and may be more beneficial for gait control than continuous stimulation, which needs to be tested in future studies.

Footnotes

BC has received travel support and unrestricted educational grants for organising CPD events from Medtronic, St. Jude Medical and Boston Scientific (manufacturers of DBS electrodes). TA has performed consultancy for and received speaking fees from Medtronic. SL has been a participant in a DBS teaching course funded by Medtronic. TF, PL and LZ have received speaking fees and travel support from Medtronic and St. Jude Medical. MS has received travel support from Medtronic and St. Jude Medical, received speaker fees from St Jude Medical and performed consultancy for St Jude Medical. PB has received fees and non-financial support from Medtronic and personal fees from Boston Scientific.

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Comprar un auto nuevo o uno usado? ¿cuál es la mejor opción?
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Llegó la hora de cambiar el automóvil y es estresante. Nos gustan los autos nuevos, pero también un auto usado requiere menor inversión. ¿Qué hacer? Aquí te ayudamos a tomar la decisión correcta.

Si piensas que la respuesta que te asegura que debes comprar un auto nuevo es que tienes el presupuesto para pagar la mensualidad y el seguro? ¡te equivocas! Tampoco lo es lucir interesante detrás del timón/volante del nuevo modelo 2015 de ese reluciente vehículo? ¡no compres impulsivamente si no quieres lamentarte después!

Hay pros y contras tanto en los autos nuevos como en los de uso y cada cual debe analizarlos teniendo en cuenta sus propias necesidades financieras y de vida. En otras palabras, tu estilo de vida cotidiano, tu bolsillo y tu puntaje crediticio son claves a la hora de tomar una decisión.

Un vehículo nuevo resulta más caro que uno usado, pero si tienes el dinero para el depósito de entrada (down payment) o un vehículo usado que puedes venderle al concesionario o a un particular, buen crédito y el presupuesto para pagar el seguro, podrás empezar a visitar con calma los concesionarios en busca de buenas ofertas e incentivos.

Un vehículo usado resulta más barato que uno nuevo y por esta razón hasta podrás hasta adquirir un modelo más bonito. Además, el seguro te costará mucho menos.

Algunos automóviles nuevos incluyen el mantenimiento gratuito para cierta cantidad de tiempo o millaje. Generalmente los reparan bastante rápido y el concesionario te presta un auto o te permite alquilar uno, generalmente, libre de costos.

Cuando compras un auto de uso estás asumiendo los problemas del dueño anterior. Pregúntate si tienes el presupuesto para pagar las reparaciones del auto usado y si puedes darte el lujo de no tener auto mientras éste está siendo reparado en el taller de mecánica.

¿Serás capaz de resistir la depreciación de un auto nuevo? Los vehículos pierden valor con el paso del tiempo y el millaje. Pero los modelos nuevos deprecian con mayor rapidez. Algunos modelos pueden perder hasta un 40% de su valor en el primer año. Así que, investiga.

? El vehículo usado deprecia muy poco.

? Con un auto nuevo vivirás con la preocupación de que lo golpeen o le estropeen la pintura en un estacionamiento.

? Con un vehículo de uso tendrás más tranquilidad mental, porque el propietario anterior ya sufrió por ti y arregló los golpecitos y rayones recibidos.

Como ves, las razones para comprar un auto nuevo o uno usado no son las mismas para todas las personas. Así que analiza bien todo lo anterior para saber si tu destino está en el concesionario de autos nuevos o en el de usados. ¡Buena suerte!

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